CARE Fertility Bulletin Board

Diane2 · 17 Mar 2004

Hi Josie

Not sure how often you come here, but just wondered how my Black Cat buddy was doing.

Diane x

Josie21 · 22 Jan 2003

Hi Diane!

Crikey, it's been a long time eh? How's wee Sophie? Not so wee I expect! Wink

I'm ok thanks. Smile

Did you notice my signature? Wink

Briony · 06 Apr 2001

Josie, that is amazing news, congratulations!!!! We were cycly buddies a VERY long time ago..... So happy for you.

Love Briony

Josie21 · 22 Jan 2003

Thank you Briony.

Aww, look at Hattie - she's adorable! Smile

As you can imagine, I'm terrified on something going wrong, but I'm 13wk+4 today & saying a prayer every day that I make it to the finishing post this time.
Skippy knows btw Wink

Oh, and its twins! Surprised

Diane2 · 17 Mar 2004

Hi Josie

Have been checking on this board from time to time to see if there was any news, and saw you had just posted and read your ticker!

I am so happy for you, its great news. Hope everything goes well over the next few months. I was 41 when I had Sophie and she was my 4th pregnancy, so hopefully its a good omen for you too.

Sophie is great, she just turned 3. I cannot believe where the time has gone.

Keep us updated!

Diane x

Josie21 · 22 Jan 2003

Thanks Diane.
Its very encouraging to hear I'm the same age you were.
I've been feeling my age for sure - been feeling so tired & am pretty sick since I stopped
my steroids. Still, a small price to pay. I think my symptoms have been exaggerated by
it being twins...
I pop in here every month or so & always look out for you and Skippy & Briony, amongst others.
Sophie looks such a big girl! Eek.
Thanks for spotting me & your good wishes petal.
Xxxx

Diane2 · 17 Mar 2004

Hi Josie

Just wondered how you were doing.

Let us know.

Love

Diane x

Josie21 · 22 Jan 2003

Hi Diane.

Thanks for asking, that's really sweet of you.

I'm ok, thanks. Smile

29 weeks today. Shocked

I will be getting my c/section date at my next hospital appt on 9 February (the c/s will be done in my 36th week). We are having a boy and a girl, so am feeling very lucky, though still very scared about assuming I will ever have my babies in my arms. We had to bite the bullet this month and buy stuff as my midwife was worrying I wouldn't have so much as a babygro when they arrive (have been too superstitious to buy anything Rolling Eyes

). At the last scan (27 weeks) they were 2 1/2 lbs each! I'm pretty uncomfortanble, being only 5ft & having a 46" waist now Shocked

& having put on 3st already! Laughing

It's not a pretty sight.

I hope you and DH are well? And Sophie? Smile

Lots of love,
Jo
xxxx

shazza10 · 25 Mar 2008

Congrats to you Jo, how wonderful having a boy and a girl, you must be sooooooooo excited!!!

Can i ask what drugs/treatment you have had eg intralipids, lit, prednisolone etc...
Best wishes
shazXXX.

Diane2 · 17 Mar 2004

Hi Jo

Glad to see that you are doing so well, hope the next few weeks go smoothly and not too uncomfortably as you prepare for your little ones to arrive. I know just how you are feeling, its hard to believe it will ever happen.

We are all fine but have had a sad 12 months as both my mum and dad have passed away. I am so thankfull that they got to meet Sophie and I spent a lot of time with them as I didn't return to work.

Sophie starts school in September, not really sure where that time has gone.

Let me know how you are doing.

Take Care

Diane x

Josie21 · 22 Jan 2003

Oh, Diane, I'm so sorry to hear that. Losing them both so close together must have been just terrible.

What happened (don't answer if that's too private)? I'm sure Sophie made such a difference to their last years. Big hugs pet.

I will try to remember to check in every couple of weeks to keep you posted. Smile

Shazza - thank you. Smile

. I was meant to be on an "in-betweeny" protocol but I had a cyst from the start
so got switched to LP. I DRd with suprefact, then stimmed with Merional & Fostimon. I also had 5 days of Clomid as E2 was
on a go-slow. I was also on dexamethazone, clexane & baby aspirin. I had ivig the day after a day 3
ET (& another one or 2 after bfp). Good luck with your tmt!

Diane2 · 17 Mar 2004

Hi Jo

No its not too private. My dad passed away after complications from a hip operation. It happened quite suddenly and was a big shock to us all. Then my mum died on New Years Day this year, she had been poorly and in and out of hospital for years but developed pneumonia just after Christmas and just couldn't fight it off.

Not sure how I would of gotten through it without Sophie, although she is getting a bit obsessed with people dying. - but she didn't seem to be too bothered about me or DH dying as she would live with Nana !!!

Hope your still doing ok, hope appt on 9th goes well. I guess your c section is the middle of March. Will be thinking of you then.

Take it easy - get lots of sleep if you can!!!

Love

Diane

Josie21 · 22 Jan 2003

Diane

That is so rough on you and your family. It is hard having the anniversary on a "special day" - my Dad died suddenly on Boxing Day 1997 and it has coloured our Christmases since. However, the good thing is that is easier for us to be together as a family and it is now a much happier day, remembering him.

I can well imagine how much Sophie has helped you.

Well, my c/s is booked for 22/3/10. Shocked

I just need them to hang on so I don't have any mad dashes up to Newcastle where we've decided to have them. At my scan last week, they were estimated at 3lb14 & 3lb12 so that's quite a comfort.

(I feel a bit naughty posting here and ruining the thread I set up for stats & reference! Embarassed

)

Jo
xxxx

Diane2 · 17 Mar 2004

Hi Jo

Just wanted to wish you all the best for the 22nd. Not long to go now, hope you make it up to Newcastle.

Give us the details when you can.

Take Care

Diane

Anna2011 · 19 Dec 2010

Hi Ladies

I thought I might revive this Poll to see if any other immune ladies might want to add their stories/stats to the Poll.
I've just had my ET and in typical 2ww fashion am trawling the forum looking for positive stories to boost my PMA!

Anna x

josephine12 · 09 Oct 2009

Good evening,

1 - Care Northampton
2 -Prednisilone, clexane, calcium and aspirin, 1 intralipid before ET and 2 after BFP.
3 - elevated th1/th2, share DQ alpha match with hubby and elevated NK cells + my hubby DNA fragmentation was not really good, so needed ISCI
4 - 3 x IUI : BFN 3 x ISCI : 1st missed miscarriage at 7 weeks, 2nd : missed miscarriage at 11.5 weeks.
3rd ISCI and 1 ISCI with immune drugs : 13 weeks pregnant with twins!

Informations : I had acupuncture every weeks, put on nearly 2stones with steroid, had a lot of proteins during stimmulation.

Good luck for your next cycle Smile

xxJosephine

Anna2011 · 19 Dec 2010

Ooh - looking good, my PMA is going up!

53% so far got a BFP on first attempt (fresh&frozen).

Josephine - congrats on the BFP with twins - amazing!!!! Am praying & hoping I will be in the same boat in a fourtnights time.

Chucy · 17 Apr 2008

Will be having immune drugs on my next cycle so interested in this poll - just bumping up to see if anyone else wants to submit a vote - Thx Lucy

Elisa · 26 Jan 2010

1. Name(s) of clinic(s) where each BFP or BFN was obtained
2. Immune drugs/dose used - and was there are different selection/dose for BFP
3. What is your Immune issue(s)
4. How many attempts before Immune drugs used
5. And anything else you feel is significant.

IM Barcelona
Intralipids, Humira, prednisolone 25 mg, clexane 40 mg
high cytokene ratios
3 attempts, 2 fresh, 1 frozen

x

MrsG · 09 Nov 2010

Hi I'm currently 6 weeks today

1. Name(s) of clinic(s) where each BFP or BFN was obtained - 3 attempts at Bourn Hall all BFNs, moved to CARE Manchester for immune tests, BFN with 1st fresh cycle, BFP with FET

2. Immune drugs/dose used - and was there are different selection/dose for BFP - Progynova, viagra, metformin, aspirin, steroids, progesterone, intralipids, calcichew, femibion

3. What is your Immune issue(s)
Massively LAD negative - Intralipids
Positive Factor V Leiden - Clexane & Aspirin
MTHFR homozygous (where the patient has two copies of the MTHFR gene) - Folic Acid, B12 & B6
Plasminogen activtor inhibitor ?? - Metformin
Raised CD19+CD5
Poor blood flow to urterus

4. How many attempts before Immune drugs used - 3

5. And anything else you feel is significant. - before my FET I had a hysetroscopy, although nothing significant found I had a good bleed afterwards and sure it helped givethe lining a good clean out

melissakitkat · 16 Apr 2010

Jazz · 14 Nov 2007

IUI 2004 x3 BFN
2007 Bath IVF 17 eggs no fertalisation
2007 Care Nottingham Trial Not suitable atigens matching.
2007 Care Nottingham ISCI with IVIG immune drugs BFN
2008 ICSI Bath no IVIG but prednisolone, clexaine, gestone and asprin BFP little boy.
2010 FET Bath Natural cycle but with lutenal support Gestone, prednisolone, clexaine and asprin. BFN
2011 FET blast Bath Madicated cycle with lutenal support gestone, prednisolone, clexaine and asprin. Ran out of Gestone so used ultragestan. BFN.

Now trying again in Czech Republic with all the same drugs but not IVIG.

Kurly · 14 Dec 2010

1. CARE Northampton
2. 10mg then 20mg Prednisolone, aspirin then Clexane, Intralipds
3. Immune system - white blood cells and natural killer cells, and clotting
4. 13 (see history .. 6 clomid - drugs only, 7 'interventions')