Endometrial Receptivity Analysis (ERA)
We can use ERA to assess the optimum time to transfer your embryo so that it has the best chance of implanting and establishing a pregnancy. The womb lining (or endometrium) is only receptive to implantation for a short period, known as the implantation window.
The main benefit of the ERA test is that we can provide a personalised embryo transfer timing, optimising the chances of implantation.
What is the ‘implantation window’?
What does ERA involve?
Could ERA be right for me?
- where you only have a single embryo available for transfer
- you are using donated gametes where the availability of future embryos is uncertain
- where embryos are being transferred to a surrogate.
Are there any risks?
The endometrial biopsy is a low-risk procedure used in many aspects of gynaecology. You may experience cramping after the procedure, and there is a small risk of infection and bleeding. There is also a minimal chance of uterine perforation. In around 5% of cases, the biopsy may not be adequate, or the tissue is unsuitable for processing, in which case the test can be repeated at no extra charge in the next cycle. ERA does not have any additional known risks for the child born due to fertility treatment.
Understanding the effectiveness of ERA
- Approximately one third of sub-fertile women could suffer from a displaced implantation window
- The ERA test has emerged as a promising tool.
- Patients with an overall good-prognosis may not benefit from ERA
- Personalised embryo transfer (pET) guided by ERA significantly increases the chances of pregnancy for non-receptive patients with recurrent implantation failure (RIF) of endometrial origin.