Pre-implantation Genetic Testing (PGT-M) allows us to test embryos before transfer for known single gene conditions
For people who know they are at increased risk of passing on a specific genetic condition, PGT-M, or (Preimplantation Genetic Testing for monogenic / single gene disorders), can be performed prior to pregnancy to greatly reduce the risk of passing the genetic condition to an affected child.
PGT-M is appropriate for people who are at high-risk of passing on a specific single gene disorder
You may be considering PGT-M if:
- You and your partner are carriers of the same autosomal recessive condition (e.g. Cystic fibrosis, Sickle Cell Disease and Beta Thalassemia)
- You are a carrier of an X-linked condition (e.g. Duchenne Muscular Dystrophy)
- You or your partner have an autosomal dominant condition (e.g. Huntington disease, Marfan Syndrome and Myotonic Dystrophy)
- You or your partner have a mutation associated with a hereditary cancer syndrome (e.g. BRCA1 & 2 or Lynch Syndrome)
- You have had a child or pregnancy diagnosed with a single gene disorder
PGT-M tests are created uniquely for each family. PGT-M can be performed for nearly any single gene disorder as long as the specific familial mutation has been identified and appropriate family members are available for test preparation where required.
It may be possible to develop a unique PGT-M test for you if you are the first person to be diagnosed with the condition in your family. All cases are assessed following referral.
PGT-M is one of the best techniques available to assist in identifying and avoiding known monogenic diseases, allowing your baby to have a healthy start in life.
Could PGT-M be helpful for me?
The PGT-M Process
1. Case Review
2. PGT-M Test Preparation
4. Embryo Biopsy
5. Embryo Freeze & Testing
6. Embryo Transfer
What conditions can PGT-M test for?
Your next step
The first step is to contact the PGT team at Care with a copy of your chromosome result to perform the initial check that imbalances arising from the translocation can be detected at the embryo stage.
If you are eligible for NHS funded treatment – please contact your local genetics service and request a referral to Care Fertility Nottingham.
If you are considering PGT privately funded treatment speak with your Insurance provider in the first instance as they may be able to provide more information about financial assistance. You can contact our PGT team using the self-referral form, providing copies of genetic reports to allow our team to provide a swift answer to your enquiry.