Reproductive and genetic health

At CARE, we offer genetic testing options for your whole reproductive pathway, helping to build healthy families from the start. 

Our whole ethos at CARE Fertility is to help people have a healthy family. For nearly 20 years, our teams have pioneered the use of Reproductive Genetics techniques, making it possible to test embryos and identify the ones with the correct number of chromosomes, or test for specific genetic diseases before the embryos are implanted.

We offer genetic testing & screening options for your whole reproductive pathway - before conception, during IVF treatments and during early pregnancy.

What is Genetic Testing?

Genetic testing is a type of medical test that identifies changes in chromosomes, genes or proteins that can cause health problems. Chromosomal abnormality is one of the most common causes of unsuccessful pregnancy. There are two types of genetic testing;

  • PGT-A (also known as PGS) is used to screen embryos for imbalances in chromosome numbers.
  • PGT-M/PGT-SR (also known as PGD) is used to detect specific inherited genetic disorders/diseases that the family are at risk of.

  

Embryo Screening for Genetic Testing

  

Embryo screening is when embryos which have already been created are tested to check they are genetically healthy. This is important as, if embryos have a genetic abnormality, such as an incorrect number of chromosomes, there is a higher chance of pregnancy loss, miscarriage, or a baby being born with a genetic condition like Down's Syndrome. Through embryo screening for genetic conditions, our embryologists can be sure to only choose embryos which are genetically normal for embryo transfer, therefore increasing the chance of you having a healthy baby.

Embryo screening can be carried out during the IVF treatment process once embryos have been created in the laboratory. Once embryos have developed to blastocysts, our embryologists can carefully remove around 5 cells from each embryo in a process called an embryo biopsy. These cells can then be tested for the genetic conditions.

At CARE, we offer embryo screening to check embryos have the correct number of chromosomes (PGT-A) and to look for specific known genetic conditions, such as Cystic Fibrosis, through PGT-M.

Our Genetic Testing Services

PGT-A (Pre-implantation Genetic Testing for Aneuploidy)

We can use PGT-A to test embryos and identify whether they have the right number of chromosomes.

PGT-A is a process where we take a few cells from an embryo during an IVF treatment cycle and test them to see whether the embryo has the correct number of chromosomes to create a healthy pregnancy. If an embryo has too many or too few chromosomes (a condition called aneuploidy) it can have a serious effect on the chances of a healthy pregnancy.

PGT-M (Pre-implantation Genetic Testing for monogenic/single gene defects)

PGT-M is used when a serious genetic disease could be passed from parent to child. This type of genetic testing is for couples where there is a known genetic condition, such as Cystic Fibrosis. It involves testing embryos created during an IVF treatment cycle and then transferring unaffected embryos.

PGT-M tests are created uniquely for each family. PGT-M can be performed for nearly any single-gene disorder as long as the specific mutation has been identified and appropriate family members are available for test preparation.

Pre-implantation testing