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Mariano Mascarenhas Consultant in Reproductive Medicine  Care Fertility Leeds

Dr Mariano Mascarenhas

Deputy Medical Director & Fertility Specialist
Dr Mariano Mascarenhas is a consultant in reproductive medicine and his primary clinical interest is in fertility preservation. His special interests include 3D ultrasound and optimising fertility pathways for women with complex medical conditions.


Mariano was the best outgoing student of his batch during under graduation in medicine at Coimbatore Medical College (best outgoing student), received the gold medal from the Prime Minister of India when finishing his obstetrics and gynaecology training in JIPMER (an institute of national importance) and fellowship in reproductive medicine in Christian Medical College (which was the first teaching hospital in India to provide an IVF service).

He received his MRCOG from the Royal College and his European Fellowship in Reproductive Medicine (EFRM) degree from ESHRE.


Mariano was a clinical fellow at Leeds for 6 years (during which time he obtained the British Fertility Society Young Clinician award) and subsequently moved to Glasgow to be a consultant. He functioned as the HFEA person responsible and as deputy medical director whilst in Glasgow and subsequently returned to Care Fertility Leeds as a consultant in reproductive medicine.

Specialities & Credentials

Mariano’s primary clinical interest is in fertility preservation and was part of a team which set up an online patient decision aid for women to navigate their fertility preservation options ( His special interests include the use of 3D ultrasound in the fertility treatment pathway and he was instrumental in setting up the 3D transvaginal ultrasound service at Leeds.

He has published over 30 papers in international peer-reviewed journals, written three book chapters, was the lead author on the British Fertility Society practice and policy paper on recurrent implantation failure and is a Cochrane author. He is the deputy to the practice and policy chair of the British Fertility Society.

He has a passion for teaching and an undergraduate project he supervised was awarded the best poster in the British Fertility Society conference in 2021.

Membership of Professional Bodies

Royal College of Obstetricians and Gynaecologists, British Fertility Society

Links to published works

  1. Kaur H, Chauhan A, Mascarenhas M. Does SARS Cov-2 infection affect the IVF outcome - A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2023 Nov 22;292:147-157.
  2. Fleming R, Mascarenhas M, Roebuck F, Ambrose P, Noble C, Henderson A, Gibson N, Gaudoin M. FSH administration at 12-hour intervals for the first 2 days, combined with mandatory GnRH-agonist trigger and blastocyst vitrification in women (<80Kg) with high AMH levels, results in higher cumulative live birth rates and is safer. Hum Fertil (Camb). 2023 Jan 16:1-8. 
  3. Jones GL, Moss RH, Darby F, Mahmoodi N, Phillips B, Hughes J, Vogt KS, Greenfield DM, Brauten-Smith G, Gath J, Campbell T, Stark D, Velikova G, Snowden JA, Baskind E, Mascerenhas M, Yeomanson D, Skull J, Lane S, Bekker HL, Anderson RA. Cancer, Fertility and Me: Developing and Testing a Novel Fertility Preservation Patient Decision Aid to Support Women at Risk of Losing Their Fertility Because of Cancer Treatment. Front Oncol. 2022 Jun 30;12:896939. 
  4. Kamath V, Purna Chacko M, Kirubakaran R, Mascarenhas M, Kamath MS. Single nucleotide polymorphism array versus karyotype for prenatal diagnosis in fetuses with abnormal ultrasound: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2022 Apr;271:235-244. 
  5. Sharpe A, Mascarenhas M, Balen A. Ethnic variation in the live birth rate and perinatal outcomes following frozen embryo transfer: an analysis of the HFEA database from 2000 to 2016. Hum Fertil (Camb). 2021 Apr 26:1-10.
  6. Mascarenhas M, Jeve Y, Polanski L, Sharpe A, Yasmin E, Bhandari HM. Management of recurrent implantation failure: British Fertility Society policy and practice guideline. Hum Fertil (Camb). 2021 Apr 5:1-25.
  7. Morris C, Rhymell R, Mascarenhas M, Bhandari HM. Ethnic and demographic variation in consenting for research in the context of fertility treatment. Human Fertility, January 2021
  8. Mascarenhas M, Kalampokas T, Sunkara SK, Kamath MS. Concordance between systematic reviews of randomized controlled trials in assisted reproduction: an overview, Human Reproduction Open, Volume 2020, Issue 4, 2020
  9. Mascarenhas M, Mehlawat H, Kirubakaran R, Bhandari HM, Choudhary M. Live birth and perinatal outcomes using cryopreserved oocytes: an analysis of the Human Fertilisation and Embryology Authority database from 2000 to 2016 using three clinical models, Human Reproduction, , deaa343, Epub December 2020
  10. Joseph T, Mascarenhas M, Karuppusami R, Karthikeyan M, Kunjummen AT, Kamath MS. Antioxidant pretreatment for male partner before ART for male factor subfertility: a randomized controlled trial, Human Reproduction Open, Volume 2020, Issue 4, 2020, hoaa050
  11. Arakkal D, Mascarenhas M, Mangalaraj AM, Karthikeyan M, Prasad JH, Kunjummen AT, Kamath MS. Comparison of Low Cost Versus Conventional Assisted Reproductive Technology Treatment: A Prospective Micro Costing Study. Fertility & Reproduction 2020 02:03, 102-107
  12. Kamath MS, Mascarenhas M, Kirubakaran R, Bhattacharya S. Number of embryos for transfer following in vitro fertilisation or intra-cytoplasmic sperm injection. Cochrane Database Syst Rev. 2020 Aug 21;8
  13. , June 2020, Pages 53-58
  14. Kamath MS, Mascarenhas M, Franik S, Liu E, Sunkara SK. Clinical adjuncts in in vitro fertilization: a growing list. Fertil Steril. 2019 Dec;112(6):978-986. 
  15. Mascarenhas M, Balen AH. Could ethnicity have a different effect on fresh and frozen embryo transfer outcomes: a retrospective study. Reprod Biomed Online. 2019 Nov;39(5):764-769
  16. Richardson A, Mascarenhas M, Balen AH. Is a woman's chronological age or 'ovarian age' more important in determining perinatal outcome after assisted reproductive treatment? Hum Fertil (Camb). 2019 Apr 30:1-7.
  17. Mascarenhas M, Kulkarni M, Balen AH. Can the ethnic differences in IVF cycle outcome be influenced by the impact of BMI? Hum Fertil (Camb). 2019 Jan 14:1-7.
  18. Mascarenhas, M. , Oliver, J. and Bhandari, H. M. (2018), Routes to parenthood for women with Turner syndrome. Obstet Gynecol.
  19. Mascarenhas M, Fox SJ, Thompson K, Balen AH. Cumulative live birth rates and perinatal outcomes with the use of time-lapse imaging incubators for embryo culture: a retrospective cohort study of 1882 ART cycles. BJOG. 2019 Jan;126(2):280-286.
  20. Kamath MS, Kirubakaran R, Mascarenhas M, Sunkara SK. Perinatal outcomes after
    stimulated versus natural cycle IVF: a systematic review and meta-analysis.
    Reprod Biomed Online. 2018 Jan;36(1):94-101.
  21. Mascarenhas M, Sunkara SK, Antonisamy B, Kamath MS. Higher risk of preterm birth and low birth weight following oocyte donation: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2017 Sep 19;218:60-67.
  22. Kamath MS, Antonisamy B, Mascarenhas M, Sunkara SK. High-risk of preterm birth and low birth weight after oocyte donation IVF: analysis of 133,785 live births. Reprod Biomed Online. 2017 Sep;35(3):318-324.
  23. Mascarenhas M, Rawnsley V, Balen A. Iron overload directly affecting the
    ovaries in a patient with Diamond-Blackfan anaemia: a case report. Hum Fertil
    (Camb). 2017 Jun 23:1-5
  24. Kamath MS, Mascarenhas M, Kirubakaran R, Nair R, Kulkarni A. Use of embryo
    culture supernatant to improve clinical outcomes in assisted reproductive
    technology: a systematic review and meta-analysis. Hum Fertil (Camb). 2017 Apr
  25. Kamath MS, Chittawar PB, Kirubakaran R, Mascarenhas M. Use of
    granulocyte-colony stimulating factor in assisted reproductive technology: A
    systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2017
    Jul;214:16-24. doi: 10.1016/j.ejogrb.2017.04.022. Epub 2017 Apr 13.
  26. Mascarenhas M, Balen AH. The high responder: a review of pathophysiology and outcomes during IVF treatment. Hum Fertil. 2017 Feb 28;0(0):1–13.
  27. Mascarenhas M, Thomas S, Kamath MS, Ramalingam R, Kongari AM, Yuvarani S, Srivastava VM, George K. Prevalence of chromosomal abnormalities and Y chromosome microdeletion among men with severe semen abnormalities and its correlation with successful sperm retrieval. J Hum Reprod Sci 2016;9:187-93
  28. Mascarenhas M, Gnanaprabha K. Monozygotic Pregnancies Following Assisted Reproductive Technology: A Review. EMJ Repro Health. 2016;2[1]:79-85
  29. Mascarenhas M, Kamath MS, Chandy A, Kunjummen AT. Progesterone/Estradiol Ratio as a Predictor in the ART Cycles with Premature Progesterone Elevation on the Day of hCG Trigger. J Reprod Infertil. 2015;16(3):155-161
  30. Kamath MS, Mascarenhas M, B K, Vasani NN, Joshi A, K M, George K. Uterine flushing with supernatant embryo culture medium in vitrified warmed blastocyst transfer cycles: a randomized controlled trial. J Assist Reprod Genet. 2015 Feb;32(2):225-31.
  31. Mascarenhas M, Kamath MS, Muthukumar K, Mangalaraj AM, Chandy A, Aleyamma T. Obstetric outcomes of monochorionic pregnancies conceived following assisted reproductive technology: A retrospective study. J Hum Reprod Sci. 2014 Apr;7(2):119-24.
  32. Mascarenhas M, Habeebullah S, Sridhar MG. Revisiting the role of first
    trimester homocysteine as an index of maternal and fetal outcome. J Pregnancy.
    2014;2014:123024. doi: 10.1155/2014/123024. Epub 2014 May 5.
  33. Sagili H, Pramya N, Prabhu K, Mascarenhas M, Reddi Rani P. Are teenage pregnancies at high risk? A comparison study in a developing country. Arch Gynecol Obstet. 2012 Mar;285(3):573-7.
  34. Dasari P, Maurya DK, Mascarenhas M. Uterine artery pseudoaneurysm: a rare cause of secondary postpartum haemorrhage following caesarean section. BMJ Case Rep. 2011 Mar 25;2011.

Book chapters:

  1. Targeting infertility in PCOS: unfolding "Ariadne's thread" Mascarenhas M, Balen AH
  2. Woodward and Mehta. Female infertility: core principles and clinical management. Chapter 11. Implantation - Mascarenhas M, Kamath MS, Sunkara SK
  3. Bricker, Robinson and Thilaganathan. Management of Multiple Pregnancy. Assisted conception and multiple pregnancy: strategies to reduce rates. Mascarenhas M, Balen AH